Spotlight on the Staffordshire Bull Terrier

The Canine Genetics Centre has worked closely with many breeds over the years, to investigate inherited disorders that represent a challenge to their health. In the first of a series of ‘Spotlight’ articles we would like to share the story of how we worked with the Staffordshire Bull Terrier community to understand the underlying genetics of two serious and debilitating diseases and develop DNA tests for them both, thus providing the tools with which to eradicate both these conditions from this much-loved breed. Continue reading

Exciting New DNA Test for Retinopathy with Vitamin E Deficiency (RVED) in Cocker Spaniels

The Canine Genetics Centre (CGC) is excited to announce the launch of a new DNA test through Canine Genetic Testing (CAGT) for Retinopathy with Vitamin E Deficiency (RVED) in Cocker Spaniels. Our discovery, made in collaboration with leading veterinary ophthalmologists, could have significant health implications for Cocker Spaniels, and not only those born in the future but potentially some that are alive today. Continue reading

Launch of DNA test for progressive retinal atrophy in the English Shepherd dog

The Canine Genetics Centre (CGC) is excited to announce the launch of a new DNA test, for progressive retinal atrophy (PRA) in the English Shepherd Dog, a breed that has shared ancestry with the Border Collie, the Rough Collie and the Australian Shepherd. Continue reading

Exercise induced paroxysmal movement disorder in Weimaraners

The Kennel Club Genetics Centre has an archive of over 40,000 DNA samples that has been collected over decades.  This collection, which contains DNA from dogs of nearly two hundred different breeds of dog, has played a central role in all the KCGC’s successful research projects.  But it has also contributed to research done by teams of researchers from other institutions. Continue reading

Multiocular defect in Old English Sheepdogs

Multiolcular defect in Old English SheepdogsIn recent years multiple dogs of the Old English Sheepdog (OES) breed have been diagnosed with an ocular (eye) disease that can affect multiple parts of the eye and is therefore known as multiocular defect (MOD). Most affected dogs suffer from cataracts, but additional abnormalities can include any of the following:

  • microphakia (small lens),
  • lens coloboma (a hole in the lens),
  • macrophthalmos (enlarged globe),
  • retinal detachment,
  • vitreopathy and
  • retinal degeneration

Continue reading