Investigating the genetics of disc calcification in Dachshunds

We have introduced Bruno Lopes to our supporters before – Bruno is a veterinary neurologist, from Southfields Veterinary Specialists, who has recently started studying for a PhD on a part-time basis at Cambridge Vet School. For his PhD, Bruno will be investigating the genetics of Intervertebral disc disease (IVDD), the most common cause of spinal injury in dogs. IVDD can affect all breeds but chondrodystrophic (short-legged) breeds are at highest risk and Dachshunds are more likely to be affected by IVDD than other breeds. Continue reading

8 runners, 4 legs, 2 teams and a Border Collie who started it all

On 1st September, two teams will be heading to London to run the Big Relay and raise funds to support the Canine Genetics Centre and its idiopathic epilepsy (IE) research. One team, who came up with the idea, was inspired by a Border Collie named Buddy; the second team is made up of CGC researchers who are eager to support the cause. Continue reading

CGC Member represents the UK at Flyball World Cup

© Hana Leisser Photography

All of the CGC team are dog lovers and most have at least one pet dog. Our Bioinformatician, Ellen, is slightly different though as she has multiple dogs and competes in the sport of flyball outside of work. Ellen has recently competed at the Flyball Open World Cup in Germany where her team came 4th in the world! Continue reading

Epilepsy study sample collection off to a flying start

Earlier this year the CGC announced the broadening of its idiopathic epilepsy (IE) project to include Beagles, English Springers, Giant Schnauzers, Hungarian Vizslas and Irish Setters. The IE team is pleased to report that the launch has met with a very enthusiastic response from dog owners: around 160 swab kits for the above five breeds have been sent out, with more kit requests coming in every day. Continue reading

Breeding with Carriers – yay or nay?

With the recent launch of the Paradoxical pseudomyotonia (PP) test in the Cocker Spaniel, we have seen an increase in breeders asking whether it is OK to breed with carrier dogs or not. This is not a simple yes/no question and we need to look at a lot more information than just the single CARRIER result that you might have received. Please read more from our experts to help you better understand this area and what is best for your personal breeding program. Continue reading

Paper detailing PRA modifier frequencies published

The Canine Genetics Centre has had an important study published, in collaboration with Wisdom Panel, on the genetics of progressive retinal atrophy in dogs. The paper describes the frequency of two genetics variants, called RPGRIP1ins44 and MAP9del, in 132 different breeds of dog. Both the variants were originally identified in Miniature Longhaired Dachshunds, and both are known to modify the development and progression of PRA. Continue reading

A Focus on Eyes

Last month we told you about an eye disease variant we recently identified in the English Shepherd Breed. Today we wanted to give you a bit more information on the research we do into inherited eye diseases (IED), all of which is now carried out under the CRIEDD (Consortium to Research Inherited Eye Diseases in Dogs ) project. Continue reading