Mutation responsible for progressive retinal atrophy in the English Shepherd published

Back in March, CAGT launched a DNA test for progressive retinal atrophy (PRA) in the English Shepherd Dog breed (PRA6). Since then we have been working on a manuscript detailing our research and we are very pleased to announce that it was published last Sunday in Genes.

Stanbury K, Schofield EC, McLaughlin B, Forman OP, Mellersh CS. Exonic Short Interspersed Nuclear Element Insertion in FAM161A Is Associated with Autosomal Recessive Progressive Retinal Atrophy in the English ShepherdGenes. 2024; 15(7):952. doi: 10.3390/genes15070952

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A Focus on Eyes

Last month we told you about an eye disease variant we recently identified in the English Shepherd Breed. Today we wanted to give you a bit more information on the research we do into inherited eye diseases (IED), all of which is now carried out under the CRIEDD (Consortium to Research Inherited Eye Diseases in Dogs ) project. Continue reading

Launch of DNA test for progressive retinal atrophy in the English Shepherd dog

The Canine Genetics Centre (CGC) is excited to announce the launch of a new DNA test, for progressive retinal atrophy (PRA) in the English Shepherd Dog, a breed that has shared ancestry with the Border Collie, the Rough Collie and the Australian Shepherd. Continue reading

Multiocular defect in Old English Sheepdogs

Multiolcular defect in Old English SheepdogsIn recent years multiple dogs of the Old English Sheepdog (OES) breed have been diagnosed with an ocular (eye) disease that can affect multiple parts of the eye and is therefore known as multiocular defect (MOD). Most affected dogs suffer from cataracts, but additional abnormalities can include any of the following:

  • microphakia (small lens),
  • lens coloboma (a hole in the lens),
  • macrophthalmos (enlarged globe),
  • retinal detachment,
  • vitreopathy and
  • retinal degeneration

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