Analysis showing an association between CPT1A and cataracts in Northern breeds published

The Canine Genetics Centre has a successful track record investigating the genetic basis of inherited eye diseases in dogs. However, some eye diseases have been more challenging to investigate than others, and cataracts have been no exception. Many breeds are predisposed to develop inherited forms of cataracts, but their inheritance is generally more complex than for other eye diseases, such as progressive retinal atrophy, so identifying underlying genetic risk factors is harder. Continue reading

Spotlight on the Staffordshire Bull Terrier

The Canine Genetics Centre has worked closely with many breeds over the years, to investigate inherited disorders that represent a challenge to their health. In the first of a series of ‘Spotlight’ articles we would like to share the story of how we worked with the Staffordshire Bull Terrier community to understand the underlying genetics of two serious and debilitating diseases and develop DNA tests for them both, thus providing the tools with which to eradicate both these conditions from this much-loved breed. Continue reading