Progressive retinal atrophy (PRA)
Canine inherited eye diseases (IEDs) affect over 160 breeds of dog and are caused by variants located in over 60 different genes. Almost half of[…]
Cambridge Vet School – One big research family!
The Canine Genetics Centre is proud to be a part of one of the UK’s leading Veterinary schools. Cambridge Vet school not only matriculates incredible[…]
A novel disease in the Segugio Italiano dog breed – our search for the causal variant
Our research project dedicated to inherited eye disease (IED) in dogs, CRIEDD, often sees us work in close collaboration with veterinary ophthalmologists. When they see[…]
Relieving the pressure of inherited glaucoma in dogs
The Canine Genetics Centre is excited to be resuming its research into primary glaucoma in dogs. This article explains what glaucoma is, and what we[…]
The TTPA variant causing retinopathy with vitamin E deficiency (RVED) is found in two more breeds of dog
In January of this year we published our research into an inherited eye disease called retinopathy with vitamin E deficiency (RVED) in English Cocker Spaniels.[…]
Primary lens luxation in the Lancashire Heeler
In 2010 we published our findings from a collaborative research project with our colleagues at the University of Missouri, into primary lens luxation (PLL) in[…]
Multiocular Defect in the Cocker Spaniel – The Next Challenge
The Cocker Spaniel is one of the most popular dog breeds in the UK and so it is unsurprising that a number of inherited diseases[…]
Watching for inherited eye disease in every dog breed
This week, we turn our focus to Dr Katherine Stanbury, who manages our inherited eye disease programme, CRIEDD (Consortium to Research Inherited Eye Disease in[…]
A Focus on Eyes
Last month we told you about an eye disease variant we recently identified in the English Shepherd Breed. Today we wanted to give you a[…]
Recent Publications
Wade CM et al. Autosomal dominant primary hyperparathyroidism in the Keeshond dog breed is strongly associated with a missense variant in sirtuin-6. Anim Genet. 2025 Dec;56(6)
Ricketts SL et al. Common variants in the CPT1A gene are associated with cataracts in Northern breeds of domestic dog. PLoS One. 2025 Apr 4
Jenkins CA et al. Genome-wide association study of idiopathic epilepsy in the Italian Spinone dog breed. PLoS One. 2025 Mar 5
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