The CGC’s research database currently consists of 41,717 samples from 215 dog breeds collected since the early 1990s for the purpose of tackling inherited canine diseases. Roughly three quarters of sample contributions have come from UK-based donors, and the remaining quarter from 46 countries around the world. Alongside the data generated by the group over the years, our sample collection is a key resource that enables researchers to determine genetic variants responsible for heritable diseases in dogs. Continue reading
News
CGC and veterinary hospital team up for innovative investigations
The two main specialist areas of focus for our work in the Canine Genetics Centre (CGC) are ophthalmology and neurology. For this week’s newsletter, Dr Sally Ricketts, Senior Research Associate, tells us about how the CGC joins forces with the Queen’s Veterinary School Hospital (QVSH) to enhance our research into these conditions. Continue reading
Chris Jenkins on Border Collie brilliance and unravelling the epilepsy enigma
This week we turn our attention to canine genetics researcher and Border Collie enthusiast Dr Chris Jenkins. Chris has worked with the CGC since the team moved to Cambridge in 2021, and before then with the same group when based at the Animal Health Trust in Suffolk. We talked to Chris about his work, and learned about how his favourite dog breed may have influenced his career choices. Continue reading
CGC’s relay runners run rings round London landmarks
On Sunday 1st September, five runners teamed up on behalf of “Team CGC” to take part in London’s Big Relay – to raise money to support the Canine Genetics Centre and its idiopathic epilepsy (IE) research. It turns out that relays involve a lot more planning than the average race (which station is nearest to which start point? What time does each runner need to be in place? Who will look after whose kit bag…?), but the preparations paid off and after an early start all five runners were at their various start points, spread out from Tower Bridge to Canary Wharf, in plenty of time and raring to go. Continue reading
Cocker Crazy at the KC International Agility Festival!
Last weekend we attended one of the largest Dog Agility shows in the UK, the Kennel Club International Agility Festival (KCIAF), where we met up with over 100 Cocker Spaniels. We were collecting data for research into Intervertebral Disc Disease (IVDD) as part of Bruno’s PhD. Continue reading
Exciting New DNA Test for Retinopathy with Vitamin E Deficiency (RVED) in Cocker Spaniels
The Canine Genetics Centre (CGC) is excited to announce the launch of a new DNA test through Canine Genetic Testing (CAGT) for Retinopathy with Vitamin E Deficiency (RVED) in Cocker Spaniels. Our discovery, made in collaboration with leading veterinary ophthalmologists, could have significant health implications for Cocker Spaniels, and not only those born in the future but potentially some that are alive today. Continue reading
Mutation responsible for progressive retinal atrophy in the English Shepherd published
Back in March, CAGT launched a DNA test for progressive retinal atrophy (PRA) in the English Shepherd Dog breed (PRA6). Since then we have been working on a manuscript detailing our research and we are very pleased to announce that it was published last Sunday in Genes.
Stanbury K, Schofield EC, McLaughlin B, Forman OP, Mellersh CS. Exonic Short Interspersed Nuclear Element Insertion in FAM161A Is Associated with Autosomal Recessive Progressive Retinal Atrophy in the English Shepherd. Genes. 2024; 15(7):952. doi: 10.3390/genes15070952
Investigating the genetics of disc calcification in Dachshunds
We have introduced Bruno Lopes to our supporters before – Bruno is a veterinary neurologist, from Southfields Veterinary Specialists, who has recently started studying for a PhD on a part-time basis at Cambridge Vet School. For his PhD, Bruno will be investigating the genetics of Intervertebral disc disease (IVDD), the most common cause of spinal injury in dogs. IVDD can affect all breeds but chondrodystrophic (short-legged) breeds are at highest risk and Dachshunds are more likely to be affected by IVDD than other breeds. Continue reading
Meet the Beagles!
Hundreds of Beagles and their owners came together on Sunday 7th July at scenic Sysonby Acres, just outside Melton Mowbray, to enjoy a day of Beagle-related events, activities and stalls. The occasion was Beagle Welfare’s 45th Anniversary Fun Day and CGC keenly accepted an invitation to attend. Continue reading
8 runners, 4 legs, 2 teams and a Border Collie who started it all
On 1st September, two teams will be heading to London to run the Big Relay and raise funds to support the Canine Genetics Centre and its idiopathic epilepsy (IE) research. One team, who came up with the idea, was inspired by a Border Collie named Buddy; the second team is made up of CGC researchers who are eager to support the cause. Continue reading
