News

The Canine Genetic Centre investigates reports of sudden death in young Labradors

Geneticists from the Canine Genetics Centre, along with veterinary cardiologists and neurologists from the Queen’s Veterinary School Hospital, are becoming increasingly concerned by reports of sudden, unexpected deaths in young Labrador Retrievers – often occurring during rest or sleep – in dogs that appeared otherwise healthy. Continue reading

Why do we publish the results of our research?

The Canine Genetics Centre (CGC) is enormously proud of its publication record. Since the year 2000 the CGC team members have published well over 100 peer-reviewed papers, the majority in open-access scientific journals with global readership. However we are often asked “why publish our results and give away our secrets”, so this week we are going to answer that very question. Continue reading

Relieving the pressure of inherited glaucoma in dogs

The Canine Genetics Centre is excited to be resuming its research into primary glaucoma in dogs. This article explains what glaucoma is, and what we are doing to resume our investigations of this painful and blinding canine disease. Continue reading

Every dog counts: let’s paint the graph yellow!

Since our last update, the CGC Idiopathic Epilepsy (IE) project has had a great response to our call for samples. A huge thank you to everyone who has sent us swabs or completed our epilepsy questionnaire, especially those of you who have been organising big batches of cheek swab DNA collection kits! Continue reading

The TTPA variant causing retinopathy with vitamin E deficiency (RVED) is found in two more breeds of dog

In January of this year we published our research into an inherited eye disease called retinopathy with vitamin E deficiency (RVED) in English Cocker Spaniels. You may  have heard of this disease before under a different name, perhaps central progressive retinal atrophy or retinal pigment epithelial dystrophy. Continue reading

Spotlight on the Gordon Setter

The Canine Genetics Centre has worked closely with many breeds over the years, to investigate inherited disorders that represent a challenge to their health. In the next of our series, we focus on the Gordon Setter, a breed that the CGC started to work alongside over 15 years ago, when a new and emerging form of late onset progressive retinal atrophy first became apparent in this breed. Continue reading

New grant secured from the Jean Lanning Foundation

The trustees of the Jean Lanning Foundation are delighted to announce a major grant to the Canine Genetics Centre (CGC) at Cambridge University to fund exciting new research.

Dr Cathryn Mellersh has linked up with Dr Alex Cagan to collaborate on a joint proposal entitled “Decoding health: The Domestic Dog as a Model for Understanding Human Disease.” Continue reading

Analysis showing an association between CPT1A and cataracts in Northern breeds published

The Canine Genetics Centre has a successful track record investigating the genetic basis of inherited eye diseases in dogs. However, some eye diseases have been more challenging to investigate than others, and cataracts have been no exception. Many breeds are predisposed to develop inherited forms of cataracts, but their inheritance is generally more complex than for other eye diseases, such as progressive retinal atrophy, so identifying underlying genetic risk factors is harder. Continue reading